FOAM for EM pharmacists November

A weekly roundup of FOAMed content for EM pharmacists.

 

ICU Physiology in 1000 Words: Pulmonary Embolism & Pulmonary Vascular Resistance: PulmCCM

Jon-Emile S. Kenny MD [@heart_lung] What if I told you that in acute pulmonary thromboembolism [PE] that the initiation of intravenous norepinephrine [NE] decreases the calculated pulmonary vascular resistance [cPVR]? Would you believe me? Certainly, you would trust that an infusion of a thrombolytic does so. Of great interest, both NE and thrombolytics decrease the cPVR [… read more] The post

 

EM Journal Update: Effects of Tranexamic Acid on Death, Disability, Vascular Occlusive Events and Other Morbidities in Patients with Acute Traumatic Brain Injury (CRASH-3): A Randomised, Placebo-Controlled Trial: Core EM

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomized, double-blind, placebo-controlled trial. The Lancet, 2018 Background Head trauma is a leading cause

 

COLCOT: The Bottom Line

In patients post-myocardial infarction, does low dose colchicine compared with placebo, reduce ischaemic cardiovascular events?

 

Route of Naloxone Administration in Opioid Overdose. NEJM Journal Watch: Emergency Medicine R…

Intramuscular naloxone works more quickly than intranasal administration of the same dose; however, there may be advantages to intranasal administration.

 

Is there a role for a single intravenous bolus dose of corticosteroid in reducing pain in Emergency Department patients with radicular back pain? CanadiEM

 

Clinical vignette A 45-year-old healthy male presents to the emergency department (ED) with a one-day history of back pain. The pain started while working out at the gym – he lifted a heavyweight above his head and felt a

 

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