What is the INR of FFP is a guest post by Jerry Altshuler, PharmD, BCCCP So fresh and so clean I frequently encounter people touting that "The INR of FFP is like 1.6 or something". Indeed I learned something similar myself at some point. It turns out however that the mean INR of FFP is actually 1.1 (Transfusion 2005;45:1234-5.). So why does it seem like no matter how much FFP you tend to give, it [...]

Balanced Crystalloids and Hyperkalemia is a guest post by Jerry Altshuler, Pharm.D., BCPS, BCCCP. With the recent publication of the SMART and SALT-ED trials, the chloride rich vs poor (balanced/buffered) crystalloid debate is back in the spotlight after a break post the original Yunos JAMA 2012 and SPLIT JAMA 2015. Something I commonly hear from internal medicine residents, however, is that LR and plasma-Lyte should DEFINITELY be avoided in the setting of hyperkalemia since they [...]