EMPOWER Episode 4 – Rapid Oral Loading of Antiepileptic Drugs (AEDs) in the Emergency Department

Listen to the podcast by clicking on the link below (link on iTunes available here):  EMPOWER Episode 4 – Rapid Oral Loading of Antiepileptic Drugs (AEDs) in the Emergency Department Show Notes: Core content from this episode discussed in: DiPiro’s Pharmacotherapy, 9th Edition, Chapter 40 Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 12th Edition,… Read More

A Line CAST Too Far: An Evaluation of the Contraindications of Class Ic Antiarrhythmics

Flecainide and propafenone are the only Class Ic antiarrhythmic drugs (AADs) available in the United States. These agents block the fast sodium channels within cardiomyocytes, thereby decreasing the rate of rise and magnitude of the action potential. This causes a slowing of conduction velocity, without increasing the effective refractory period. While these agents are particularly… Read More