Physostigmine: The Drug The Dogma and the Real Story
Physostigmine: The Drug The Dogma and the Real Story, guest post by Rachel Schult, Pharm.D. Physostigmine is a reversible cholinesterase inhibitor used in the management of antimuscarinic toxicity. It differs from pharmacologically similar medications, such as neostigmine and pyridostigmine, due to its tertiary amine structure, which facilitates entry into the central nervous system. By crossing the blood-brain barrier, we can expect it to be effective for the reversal of both peripheral and central signs of [...]