Kcentra Administration Revisited

Kcentra Administration Revisited In an earlier post, the nuances associated with the administration of Kcentra was discussed. One point of contingency was associated with the dilution and rate of infusion of Kcentra. The package insert provides the following information with regards to the rate of administration: "Administer by intravenous infusion at a rate of 0.12 mL/kg/min (approximately 3 units/kg/min) up to a maximum rate of 8.4 mL/min (approximately 210 units/min)." The package insert also provides [...]

By |2019-11-24T17:41:03-05:00September 26th, 2013|EM PharmD|2 Comments

Acute Pain Management in the Emergency Department Part II

Paging Goldilocks to the ER: Acute Pain Management in the Emergency Department, Part II In an earlier post, I discussed some of the nuances associated with the administration of opioid analgesics (particularly morphine and hydromorphone) in the emergency department. This post will review some of the studies that have been recently conducted to evaluate the safety and efficacy of these agents for acute pain management in patients who present to the emergency department.    Hydromorphone: [...]

By |2019-11-24T17:41:04-05:00September 5th, 2013|EM PharmD|0 Comments