Hypercalcemia: Pamidronate vs Zoledronic acid

We use IV bisphosphonates in acute hypercalcemia with theunderstanding that they’ll help achieve a normal calcium level in about 72hours.  Aside from the importantcomponents of this treatment that will have more of an immediate effect (fluid,diuretics, steroids, calcitonin); which bisphosphonate is best? Since oral bisphosphonates have extremely low bioavailablity(1-2%), IV agents like pamidronate and zoledronic… Read More