Looking for a single dose, no compliance issues, inexpensive, safe, and effective option to treat urinary tract infections? An older therapeutic option might be the answer. A recent systematic review by Goodlet et al. looks into the utility of single dose aminoglycosides (AGs) to treat cysitis.1 Article A Systematic Review of Single-Dose Aminoglycoside Therapy for Urinary Tract Infection: Is It Time To Resurrect an Old Strategy?Kellie J. Goodlet, PharmD , Fatima Z. Benhalima, and Michael [...]
Zahra Nasrazadani, PharmD, BCPS Emergency Medicine Clinical Pharmacist Salina Regional Health Center A few months ago, Kristina Kipp wrote her inaugural EMCrit article enumerating her (extremely justified) concerns with the data we had available at the time regarding andexanet alfa…or should I say “coagulation factor Xa (recombinant), inactivated-zhzo”(1)? Since then—and in a somewhat perverse order of operations—the drug has been rolled out in a second-generation release and later, the New England Journal of Medicine published [...]
Next in the High-Yield MED Reviews giveaway: Apixaban or Rivaroxaban: The Jury’s Still out
Next in the High-Yield MED Reviews giveaway: The 5 Types of Interviewees: Reflections of a PGY-1 Resident
Next up in the High-Yield MED Reviews giveaway, "How to Wean a Guy (after at least) 10 days"
First entry in the High-Yield MED Reviews BCCCP give away - Antidote For Isoniazid-Induced Seizures.
An 80-year-old male arrived at the Emergency Department (ED) in a serious condition: he was coughing up blood. Although he coughed up about three tablespoons (50cc/hr), he was hemodynamically stable. A physician approached me with an unfamiliar question: “Could we give him nebulized TXA?” I looked at him for a moment, nonplussed. “What?!” I exclaimed, “Hold on—let me look it up and get back to you.” Questions flooded my mind: Is it effective? Is it [...]
Nausea and vomiting is a common chief complaint in the ED, one I never really paid much attention to unless prompted (appropriate agent to use in pregnancy, which medication to use for a patient with a prolonged QTc, etc.) - at least, that was my practice before I began practicing in Miami. In one of the many unforgettable cases I have had in the ED, there was a young patient who presented with nausea and vomiting. [...]
We have all been there, a patient with so many complicating factors that it’s difficult to choose the least worst option to treat a urinary tract infection. For example: a patient with a CrCl ~22 ml/min, a prolonged QTc, sulfa allergy (described as immediate death), and amoxicillin allergy (also somehow described as immediate death) who absolutely refuses to try a cephalosporin. How is it this difficult to treat a simple urinary tract infection?!?!?! There is [...]
In two previous post, I outlined my impressions of High-Yield Med Reviews based on my experience going through the modules and webinar. While I still stand behind my evaluation of HYMR, my assessment was somewhat limited because it was all before the exam. Now that I have my scores, I feel I can give a more complete assessment of HYMR. In a nutshell: I passed, and highly recommend HYMR. In the final days before the exam, [...]